Prof. Dr. Burak GÜÇLÜ

Neuroscience & Neuroengineering

+90 216 516 34 67
+90 216 516 34 79
Burak Güçlü received a B.S. degree in Control and Computer Engineering from İstanbul Technical University in 1997 and an M.S. degree in Bioengineering from Syracuse University in 1999. He worked as a teaching assistant for Biocontrol Systems and Bioinstrumentation Laboratory. He recorded from tactile nerve fibers of cats at Institute for Sensory Research (ISR) in Syracuse, New York. In 1999-2000, Dr. Güçlü attended University of Michigan in Ann Arbor and studied sensory systems of insects at Advanced Technology Laboratories, and of guinea pigs at Kresge Hearing Research Institute using multi-electrodes. Then, he returned to ISR and worked on mathematical modeling of the sense of touch. He performed psychophysical experiments on human subjects and tested computational models. He received his Ph.D. degree in Neuroscience from Syracuse University in 2003. During his post-doctoral year, he studied species-specific vocalizations and recorded from the prefrontal cortex of awake-behaving macaque monkeys in the medical school of University of Rochester. Dr. Güçlü has been with Institute of Biomedical Engineering at Boğaziçi University since 2004. He is the director of Tactile Research Laboratory at the Institute and has founded the University Vivarium in Center for Life Sciences and Technologies Research. His research focuses on the transformation of tactile information from the periphery to the cortex. It involves electrophysiological recordings from rat S1, human psychophysics, and modeling. He has recently completed a project to develop cortical neuroprostheses for tactile feedback, and is associated with an EU consortium on graphene electrodes for novel neural interfaces.
Research Areas
Tactile physiology and psychophysics
Computational neuroscience
Sensory Systems
Biomedical instrumentation
Recently Published !!!

Project Grants

Co-investigator (2018- ): GRAphene-based Flexible neural Interfaces for the control of Neuroprosthetic devices (EU FLAG-ERA JTC-2017, PI: Navarro)

Principal investigator (2017-2021): Attentional mechanisms in the rat somatosensory cortex (BU grant no: 17XP2)

Principal investigator (2015-2016): Psychophysical equivalence for tactile and intracortical electrical stimulation (BU grant no: 15XD2)

Principal investigator (2014-2017): Somatosensory cortical processing and neuroprosthesis design for the rat (TÜBİTAK grant no: 113S901)

Principal investigator (2013-2017): Excitation-inhibition balance in somatosensory cortical neurons (BU grant no: 13XP8)

Principal investigator (2010-2013): Spatial effects of mechanical stimulation on tactile nerve fibers (BU grant no: 10XP1)

Coordinator for University Vivarium (2009-2012): Center for Life Sciences and Technologies Research (DPT grant no: 2009K120520, PI: Barbarosoğlu)

Principal investigator (2007-2009): Physiological correlates of excessive computer gaming in young adults (BU grant no: 07HX103)

Co-investigator (2005-2008): Morphological organization of cutaneous mechanoreceptors (NIH grant no: NS036816, PI: Verrillo)

Principal investigator (2005-2008): The relationship between psychophysical response and evoked potentials in the sense of touch (TÜBİTAK grant no: 104S228)

Principal investigator (2004-2007): Analysis of human sensory function. I. Touch (BU grant no: 04HX101)

Post-doctoral fellow (2003-2004): Auditory & integrative processes in prefrontal cortex (NIH grant no: DC004845, PI: Romanski)

Research assistant (2000-2003): Morphological organization of cutaneous mechanoreceptors (NIH grant no: NS036816, PI: Bolanowski)

Research assistant (1999-2000): Multichannel silicon electrodes in neural prostheses: Visual, auditory & motor (NIH grant no: RR009754, PI: Anderson)

Research assistant (1998): Neural intensity effects-Tactile (NIH grant no: DC00080, PI: Bolanowski)

Journal Articles

Gök Ç, Devecioğlu İ, Güçlü B (2022) Mechanical impedance of rat glabrous skin and its relation with skin morphometry. J Biomech Eng - T ASME. 144: 021001 (10 pp).

Birgul İyison N, Devlet Kiliçkap B, Duan Sahbaz B, Vardar B, Güçlü B (2021) Distribution and mRNA expression of nAChRs in the rat S1 and M1 cortices after electrical stimulation of the basal forebrain. Turk Neurosurg. 31: 896-906.

Jamalzadeh M, Basdogan C, Güçlü B (2021) Effect of remote masking on tactile perception of electrovibration. IEEE Trans Haptics. 14: 132-142.

Devecioğlu İ, Güçlü B (2020) Psychophysical detection and learning in freely behaving rats: A probabilistic dynamical model for operant conditioning. J Comput Neurosci. 48: 333-353.

Vardar B, Güçlü B (2020) Effects of basal forebrain stimulation on the vibrotactile responses of neurons from the hindpaw representation in the rat SI cortex. Brain Struct Funct. 225: 1761-1776.

Karakuş İ, Güçlü B (2020) Psychophysical principles of discrete event-driven vibrotactile feedback for prostheses. Somatosens Mot Res. 37: 186-203.

Öztürk S, Devecioğlu İ, Beygi M, Atasoy A, Mutlu Ş, Özkan M, Güçlü B (2019) Real-time performance of a tactile neuroprosthesis on awake behaving rats. IEEE Trans Neural Syst Rehabil Eng. 27: 1053-1062.

Vardar Y, Güçlü B, Basdogan C (2018) Tactile masking by electrovibration. IEEE Trans Haptics. 11: 623-635.

Vardar Y, Güçlü B, Basdogan C (2017) Effect of waveform on tactile perception by electrovibration displayed on touch screens. IEEE Trans Haptics. 10: 488-499.

Vardar B, Güçlü B (2017) Non-NMDA receptor-mediated vibrotactile responses of neurons from the hindpaw representation in the rat SI cortex. Somatosens Mot Res. 34: 189-203.

Kaya MS, Güçlü B, Schimmel M, Akyüz S (2017) Two-colour chewing gum mixing ability test for evaluating masticatory performance in children with mixed dentition: validity and reliability study. J Oral Rehabil. 44: 827-834.

Quindlen JC, Güçlü B, Schepis EA, Barocas VH (2017) Computational parametric analysis of the mechanical response of structurally varying Pacinian corpuscles. J Biomech Eng - T ASME. 139: 071012 (9 pp).

Kaya MS, Akyuz S, Guclu B, Diracoglu D, Yarat A (2017) Masticatory parameters of children with and without clinically diagnosed caries in permanent dentition. Eur J Paediatr Dent. 18: 116-120.

Devecioğlu İ, Güçlü B (2017) Psychophysical correspondence between vibrotactile intensity and introcortical microstimulation for tactile neuroprostheses in rats. J Neural Eng. 14: 016010 (17 pp).

Beygi M, Mutlu S, Güçlü B (2016) A microfabricated strain gauge array on polymer substrate for tactile neuroprostheses in rats. J Micromech Microeng. 26: 084006 (12 pp).

Yıldız MZ, Toker İ, Özkan FB, Güçlü B (2015) Effects of passive and active movement on vibrotactile detection thresholds of the Pacinian channel and forward masking. Somatosens Mot Res. 32: 262-272.

Kuyumcu F, Erdogan Ö, Güçlü B (2015) Electrical nerve stimulation method for intraoperative localization of the inferior alveolar nerve within the mandible: A pilot study in rabbits. Int J Oral Max Surg. 44: 1398-1404.

Güçlü B, Tanıdır C, Çanayaz E, Güner B, İpek Toz H, Üneri ÖŞ, Tommerdahl M (2015) Tactile processing in children and adolescents with obsessive-compulsive disorder. Somatosens Mot Res. 32: 163-171.

Devecioğlu İ, Güçlü B (2015) A novel vibrotactile system for stimulating the glabrous skin of awake freely behaving rats during operant conditioning. J Neurosci Meth. 242: 41-51.

Güçlü B, Çelik S, Ilci C (2014) Representation of haptic objects during mental rotation in congenital blindness. Percept Mot Skills. 118: 587-607.

Aşik MD, Yaprak B, Güven E, Karabulut AB, Güçlü B (2013) A device for the functional improvement of lagophthalmos. J Craniofac Surg. 24: 1478-1482.

Ayyildiz M, Güçlü B, Yildiz MZ, Basdogan C (2013) An optoelectromechanical tactile sensor for detection of breast lumps. IEEE Trans Haptics. 6: 145-155.

Yildiz MZ, Güçlü B (2013) Relationship between vibrotactile detection threshold in the Pacinian channel and complex mechanical modulus of the human glabrous skin. Somatosens Mot Res. 30: 37-47.

Devecioğlu İ, Güçlü B (2013) Asymmetric response properties of rapidly adapting mechanoreceptive fibers in the rat glabrous skin. Somatosens Mot Res. 30: 16-29.

Güçlü B, Dinçer ŞM (2013) Neural coding in the Non-Pacinian I tactile channel: A psychophysical and simulation study of magnitude estimation. Somatosens Mot Res. 30: 1-15.

Güçlü B, Ertaç S, Hortaçsu A, List JA (2012) Mental attributes and temporal brain dynamics during bargaining: EEG source localization and neuroinformatic mapping. Soc Neurosci. 7: 159-177.

Dıraçoğlu D, Alptekin K, Çifter ED, Güçlü B, Karan A, Aksoy C (2011) Relationship between maximal bite force and tooth wear in bruxist and non-bruxist individuals. Arch Oral Biol. 56: 1569-1575.

Güçlü B, Sevinc E, Canbeyli R (2011) Duration discrimination by musicians and nonmusicians. Psychol Rep. 108: 675-687.

Press D, Mutlu S, Güçlü B (2010) Evidence of fast serotonin transmission in frog slowly adapting type 1 responses. Somatosens Mot Res. 27: 174-185.

Pawson L, Prestia LT, Mahoney GK, Güçlü B, Cox PJ, Pack AK (2009) GABAergic/glutamatergic-glial/neuronal interaction contributes to rapid adaptation in Pacinian corpuscles. J Neurosci. 29: 2695-2705.

Utine CA, Güçlü B, Perente İ, Farell B (2009) Glokomda eşik-üstü kontrast algılanması. MN Ophthalmology. 16: 84-91.

Dıraçoğlu D, Güçlü B, Alptekin K, Karan A, Aksoy C (2008) Maximal bite force measurement by the “Istanbul Bite Force Recorder”. J PMR Sci. 11(3): 117-123.

Güçlü B, Mahoney GK, Pawson LJ, Pack AK, Smith RL, Bolanowski SJ (2008) Localization of Merkel cells in the monkey skin: An anatomical model. Somatosens Mot Res. 25: 123-138.

Güçlü B, Öztek Ç (2007) Tactile sensitivity of children: Effects of frequency, masking, and the Non-Pacinian I psychophysical channel. J Exp Child Psychol. 98: 113-130.

Güçlü B (2007) Deviation from Weber's law in the Non-Pacinian I tactile channel: A psychophysical and simulation study of intensity discrimination. Neural Comput. 19: 2638-2664.

Güçlü B, Murat A (2007) Active touch does not improve sequential processing in a counting task. Acta Neurobiol Exp. 67: 165-169.

Güçlü B, Tanidir C, Mukaddes NM, Ünal F (2007) Tactile sensitivity of normal and autistic children. Somatosens Mot Res. 24: 21-33.

Güçlü B (2007) Low-cost computer-controlled current stimulator for the student laboratory. Adv Physiol Educ. 31: 223-231.

Güçlü B, Schepis EA, Yelke S, Yucesoy CA, Bolanowski SJ (2006) Ovoid geometry of the Pacinian corpuscle is not the determining factor for mechanical excitation. Somatosens Mot Res. 23: 119-126.

Gescheider GA, Güçlü B, Sexton JL, Karalunas S, Fontana A (2005) Spatial summation in the tactile sensory system: Probability summation and neural integration. Somatosens Mot Res. 22: 255-268.

Güçlü B, Gescheider GA, Bolanowski SJ, Istefanopulos Y (2005) Population-response model for vibrotactile spatial summation. Somatosens Mot Res. 22: 239-253.

Güçlü B (2005) Maximizing the entropy of histogram bar heights to explore neural activity: A simulation study on auditory and tactile fibers. Acta Neurobiol Exp. 65: 399-407.

Güçlü B, Bolanowski SJ (2005) Vibrotactile thresholds of the Non-Pacinian I channel: II. Predicting the effects of contactor location on the phalanx. Somatosens Mot Res. 22: 57-68.

Güçlü B, Bolanowski SJ (2005) Vibrotactile thresholds of the Non-Pacinian I channel: I. Methodological issues. Somatosens Mot Res. 22: 49-56.

Güçlü B, Farell B (2005) Influence of target size and luminance on the White-Todorović effect. Vision Res. 45: 1165-1176.

Güçlü B, Bolanowski SJ (2004) Tristate Markov model for the firing statistics of rapidly-adapting mechanoreceptive fibers. J Comput Neurosci. 17: 107-126.

Güçlü B, Engbretson GA, Bolanowski SJ (2004) Constrained optimization of Drude's equations eliminates effects of confounding molecules for the polarimetric measurement of glucose. J Biomed Opt. 9: 967-977.

Güçlü B, Bolanowski SJ (2004) Probability of stimulus detection in a model population of rapidly adapting fibers. Neural Comput. 16: 39-58.

Güçlü B, Bolanowski SJ (2003) Frequency responses of cat rapidly adapting mechanoreceptive fibers. Somatosens Mot Res. 20: 249-263.

Güçlü B, Bolanowski SJ (2003) Correlation of spatial event plots with simulated population responses of mechanoreceptive fibers. Somatosens Mot Res. 20: 199-208.

Güçlü B, Bolanowski SJ, Pawson L (2003) End-to-end linkage (EEL) clustering algorithm: A study on the distribution of Meissner corpuscles in the skin. J Comput Neurosci. 15: 19-28.

Güçlü B, Bolanowski SJ (2003) Distribution of the intensity-characteristic parameters of cat rapidly adapting mechanoreceptive fibers. Somatosens Mot Res. 20: 149-155.

Güçlü B, Bolanowski SJ (2002) Modeling population responses of rapidly-adapting mechanoreceptive fibers. J Comput Neurosci. 12: 201-218.


Somatosensory Feedback for Neuroprosthetics

Population Models for the Sense of Touch: a study on rapidly-adapting mechanoreceptive fibers

Biomedical Instrumentation Laboratory Manuals


BM 502 Introduction to Physiology

BM 507 Biomedical Instrumentation Laboratory

BM 538 Computational Neuroscience

BM 632 Sensory Systems

BM 633 Dynamics of Neural Systems

PHYS 48M Biophysics

EE 580 Fundamentals of Computational Neuroscience


Tactile Research Laboratory

University Vivarium


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